Definition of Peritoneal

Peritoneal: Having to do with the peritoneum.

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    MRIs Safe With Older Pacemakers, Study Finds

    News Picture: MRIs Safe With Older Pacemakers, Study FindsBy Steven Reinberg
    HealthDay Reporter

    WEDNESDAY, Dec. 27, 2017 (HealthDay News) — Powerful magnetic fields created during an MRI scan were thought to play havoc with some pacemakers, but a new study says these scans are safe for people with the heart devices.

    Researchers tested the safety of MRIs on more than 1,500 people who had older pacemakers or implantable defibrillators — called legacy devices — that the U.S. Food and Drug Administration does not consider safe for MRIs. The result: No long-term adverse effects were found.

    “Many patients have implanted pacemakers or defibrillators that were not designed to be used with MRI scans,” said senior study author Dr. Henry Halperin. He’s a professor of medicine and co-director of the Johns Hopkins Imaging Institute of Excellence in Baltimore.

    A majority of people who have these devices will need an MRI at some point, he noted. The study results show that “it’s really safe to do MRIs in these patients,” he added.

    When MRIs were first introduced, problems with scanning those patients with implanted devices did exist, according to Halperin.

    “There were some real issues, like the devices would stop working, and there were 13 to 15 deaths reported,” he said. Based on those reports, the FDA said that people with these devices should not have MRIs.

    Since 2000, devices have been modified to make them safe during an MRI. But many people still have legacy devices that the FDA does not consider MRI-safe.

    MRIs are also safe for people who have wires that connect the devices to the heart — called leads — left in place after new leads were implanted, Halperin added.

    According to Dr. Byron Lee, a professor of medicine and director of electrophysiology laboratories and clinics at the University of California, San Francisco, “This is important research that affects patient care immediately.” Lee was not involved with the new study but was familiar with the findings.

    “Contrary to the official word from the device manufacturers and many doctors, almost all patients with pacemakers and defibrillators, and even those with older-generation devices, can get MRIs,” Lee said.

    To do the scan safely, however, special equipment and extra personnel are required, he explained.

    “Currently, many facilities cannot or choose not to provide this service,” Lee said. “Therefore, patients sometimes need to advocate for themselves and push for referral to capable centers.”

    For the study, Halperin and his colleagues tested the safety of MRIs in just over 1,500 people who needed an MRI to diagnose various conditions. However, they had either a pacemaker or an implantable defibrillator not considered to be safe for MRIs.

    Before the scans, the investigators changed the pace setting on pacemakers or the defibrillating mode on implanted defibrillators so they would not react to the electromagnetic field created by the MRI.

    Halperin’s team found no long-term significant problems when the devices were reset after the scan.

    In one patient, the battery in the pacemaker was near its expiration date and could not be reset. This patient had a new pacemaker implanted, the study authors noted.

    Although some patients experienced changes in the pacemakers’ function, these changes were not life-threatening or significant and did not require the device to be reset, the researchers said.

    Dr. Saman Nazarian, the study’s first author, said, “Given the results of our study and others, it is hard to understand the position of the Centers for Medicare and Medicaid Services to restrict access to MRIs in patients with implanted pacemakers and defibrillator systems.”

    Limiting people with legacy pacemakers and defibrillators from access to the potentially lifesaving diagnostic data attainable from an MRI is outdated, said Nazarian, who is associate professor of medicine at the University of Pennsylvania Perelman School of Medicine.

    “If you are one of the millions of patients with a pacemaker or defibrillator system in place and have been told you need an MRI, contact a center with the expertise to enable the imaging,” he said.

    The study was published in the Dec. 28 issue of the New England Journal of Medicine.

    Copyright © 2017 HealthDay. All rights reserved.

    SOURCES: Henry Halperin, M.D., professor, medicine, and co-director, Johns Hopkins Imaging Institute of Excellence, Baltimore; Saman Nazarian, M.D., Ph.D., associate professor, medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia; Byron Lee, M.D., professor, medicine, director, electrophysiology laboratories and clinics, University of California, San Francisco; Dec. 28, 2017, New England Journal of Medicine

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      Scientists Turn Skin Cells Into Muscle Cells, a Potential Boon for Research

      News Picture: Scientists Turn Skin Cells Into Muscle Cells, a Potential Boon for Research

      Latest Prevention & Wellness News

      TUESDAY, Jan. 9, 2018 (HealthDay News) — In a potential advance for medical research, scientists say they’ve created the first functioning human muscle from skin cells.

      The breakthrough could lead to better genetic or cell-based therapies, as well as furthering investigations into the causes and treatment of muscular disorders, the Duke University team said.

      “The prospect of studying rare diseases is especially exciting for us,” Nenad Bursac, professor of biomedical engineering, said in a university news release.

      “When a child’s muscles are already withering away from something like Duchenne muscular dystrophy, it would not be ethical to take muscle samples from them and do further damage,” he explained.

      “But with this technique, we can just take a small sample of non-muscle tissue — like skin or blood — revert the obtained cells to a pluripotent state, and eventually grow an endless amount of functioning muscle fibers to test,” Bursac said.

      According to the researchers, it might also be possible to fix genetic defects in pluripotent stem cells from a patient and then grow small patches of healthy muscle that could be used with other genetic treatments to heal or replace specific areas of diseased muscle.

      Of course, much more research is needed before any such therapies could be used in humans.

      In the new study, skin cells were reprogrammed in the lab to revert to what are called pluripotent stem cells — cells that can grow into any type of cell.

      The cells were then cultured while being exposed to a molecule called Pax7, which signaled the cells to start turning into muscle.

      The cells then grew into functioning skeletal muscle. According to Bursac’s team, the lab-grown cells were not as strong as those found in normal muscle tissue. However, after up to four weeks in the special lab culture, the newly formed muscle cells contracted and reacted to external stimuli much like regular muscle tissue.

      The lab-grown muscle fibers were also implanted into mice and appeared to integrate into the rodents’ natural muscle tissue, the investigators said.

      The study was published online Jan. 9 in the journal Nature Communications.

      — Robert Preidt

      Copyright © 2018 HealthDay. All rights reserved.

      SOURCE: Duke University, news release, Jan. 9, 2018

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        Annual Flu Pictures Assist Hold Seniors Out of the Hospital

        News Picture: Annual Flu Shots Help Keep Seniors Out of the HospitalBy Maureen Salamon
        HealthDay Reporter

        Newest Senior Well being Information

        MONDAY, Jan. eight, 2018 (HealthDay Information) — The present flu season is shaping as much as be a nasty one, however there’s excellent news for American seniors who’ve gotten their flu shot.

        New analysis exhibits that for older adults, faithfully getting the vaccine every year vastly reduces the percentages of catching a flu so extreme that it lands you within the hospital.

        Researchers discovered that repeated influenza vaccination gives a double profit in older adults, proving 74 p.c efficient in stopping intensive-care (ICU) admissions and 70 p.c efficient in stopping deaths.

        The findings bolster the notion that though getting a flu shot does not at all times stop the flu, it might make it milder for many who do catch it, mentioned research writer Dr. Jesus Castilla. He is a researcher on the Navarra Institute for Well being Analysis in Pamplona, Spain.

        “We have been stunned by the large magnitude of the vaccine impact in stopping extreme influenza,” Castilla mentioned. “Our outcomes present the significance of annual vaccination for stopping extreme influenza within the older inhabitants.”

        “The prevention of extreme influenza was primarily noticed in sufferers repeatedly vaccinated in each the present and former [flu] seasons, which reinforces the advice of annual influenza vaccination within the aged,” he added.

        Tens of millions of People catch the flu yearly, leading to a whole bunch of 1000’s of hospitalizations, in response to the U.S. Facilities for Illness Management and Prevention. Flu-related deaths ranged from 12,000 to 56,000 yearly between 2010 and 2017, in response to CDC estimates.

        Older adults, whose immune techniques aren’t as strong, are extra liable to struggling extreme outcomes from flu an infection, together with hospitalization, problems and dying, Castilla famous.

        “Annual vaccination acts as a booster for his or her immune response,” he mentioned. “In different phrases, the safety will increase as in comparison with the impact of vaccination in a single season.”

        The brand new analysis by Castilla and his colleagues concerned a whole bunch of hospitalized sufferers, older than 65, who had influenza — each extreme and fewer extreme instances — in addition to those that didn’t.

        Individuals who’d gotten a flu vaccination within the present and three earlier flu seasons have been half as more likely to develop a extreme case of the flu, the research discovered.

        “I feel it is reassuring that what we advocate individuals to do — which is to get vaccinated yearly — really does present some extra safety,” mentioned Dr. Marci Drees, who was not concerned with the brand new research. She’s an an infection prevention officer and hospital epidemiologist with Christiana Care Well being System in Wilmington, Del.

        “An important take-home message is to get your flu shot and never fear about how efficient it’s this 12 months,” Drees added, referring to issues that the present U.S. vaccine could be solely marginally efficient.

        “Individuals could be extra inclined to skip it, however this research actually emphasizes main profit is 12 months after 12 months of persistently getting that flu shot helps hold individuals out of the hospital and ICU,” she mentioned.

        Growing every year’s flu vaccine is a difficult enterprise, Drees defined. Well being officers within the Northern Hemisphere examine what strains of the virus circulated most generally within the Southern Hemisphere in earlier months after which adapt the vaccine to these expectations.

        “They should do some little bit of guesswork . . . and do not at all times guess appropriately,” she mentioned.

        Latest research present that flu vaccination cuts the chance of flu sickness by 40 to 60 p.c among the many common inhabitants.

        Drees mentioned she’d prefer to see analysis concentrate on youthful populations, together with kids, to find out if comparable safety is conferred after repeated vaccinations.

        “You are boosting your immune system each time you get that vaccination,” she mentioned. “We all know immunity wanes extra shortly in older individuals, so getting that increase 12 months after 12 months might be contributing to the safety we have seen towards extreme illness.”

        The research is revealed on-line Jan. eight within the journal CMAJ.

        Copyright © 2018 HealthDay. All rights reserved.

        SOURCES: Jesus Castilla, M.D., Ph.D., researcher, Navarra Institute for Well being Analysis, Pamplona, Spain; Marci Drees, M.D., M.S., an infection prevention officer and hospital epidemiologist, Christiana Care Well being System, Wilmington, Del.; CMAJ, Jan. eight, 2018, on-line

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          One other Legacy of Terror Assaults: Migraines

          News Picture: Another Legacy of Terror Attacks: MigrainesBy Amy Norton
          HealthDay Reporter

          WEDNESDAY, Dec. 13, 2017 (HealthDay Information) — Survivors of terror assaults could also be vulnerable to creating frequent migraines or tension-type complications, a brand new examine suggests.

          Norwegian researchers examined the aftermath of a 2011 terrorist assault on a summer season camp in Norway that left 69 folks useless and 33 severely wounded. Many of the useless have been youngsters.

          The investigators adopted greater than 200 of the younger survivors, taking a look at what number of have been struggling recurrent complications. They discovered that many have been — and at a fee a lot greater than could be anticipated within the normal inhabitants.

          Particularly, the teenagers had a three-times greater fee of weekly or each day complications.

          “We discovered that the survivors extra typically endure from complications as in comparison with controls, with extra frequent and extreme complaints resembling migraine,” mentioned the examine’s lead researcher, Dr. Synne Stensland, of the Norwegian Heart for Violence and Traumatic Stress Research in Oslo.

          In accordance with Stensland, the findings might have far-reaching implications.

          “We have to acknowledge that survivors of terror — and most probably different excessive violence — could also be fighting extreme headache complaints,” she mentioned.

          When that is the case, Stensland added, the complications would seemingly “have an effect on their capacity to manage within the aftermath of occasions.”

          Early therapy of migraines and stress complications might forestall them from changing into power, she famous.

          For the examine, Stensland and her colleagues in contrast 213 assault survivors with greater than 1,700 youngsters who had not skilled a terror assault. They served as “controls.” Every survivor was matched with eight teenagers of the identical age and gender.

          In interviews 4 to 5 months after the assault, the survivors have been requested about any complications they’d had prior to now three months. That, the researchers mentioned, is previous the standard time for “acute stress reactions” — that are often short-term and might be thought-about “regular.”

          General, a 3rd of the ladies have been affected by migraines, in contrast with 12 p.c of ladies within the comparability group. Amongst boys, 13 p.c of survivors had migraines, versus four p.c within the comparability group.

          Rigidity-type complications have been much more frequent, affecting half of feminine survivors and 28 p.c of male survivors.

          General, terror assault survivors had a three- to four-times greater threat for each varieties of headache, the examine discovered. That was the case even when different components, resembling previous publicity to violence, have been thought-about.

          In accordance with Stensland, the disparity primarily confirmed up in charges of frequent headache. About 12 p.c of feminine survivors and 5 p.c of male survivors had each day complications. Nevertheless, each day complications have been unusual within the comparability group — affecting 1 to 2 p.c.

          The examine was revealed on-line Dec. 13 within the journal Neurology.

          Dr. Matthew Robbins is director of inpatient companies at Montefiore Headache Heart in New York Metropolis. He mentioned, “We all know traumatic life occasion can result in a brand new headache dysfunction, or make an current one even worse.”

          This examine, he mentioned, highlights the affect of publicity to excessive violence, at a susceptible time in life.

          Even below regular circumstances, ladies are extra liable to migraines — and that begins to emerge within the teenage years, Robbins mentioned. The notably excessive fee of headache issues in feminine terror survivors appears to replicate an “excessive” model of that standard sample.

          And whereas the examine targeted on the aftermath of a mass killing, many individuals expertise smaller-scale violence or abuse, Robbins identified.

          He mentioned it is already really useful that docs display headache sufferers for any historical past of abuse. Sufferers “should not hesitate” to convey up these experiences, he added.

          In any case, therapy of recurrent complications ought to ideally contain treatment and non-drug, behavioral approaches, in accordance with Robbins.

          And in circumstances the place trauma is an element, he mentioned, there’s “little question” that must be addressed in therapy.

          Why would trauma set off or worsen recurrent complications?

          “If we’re uncovered to an especially violent occasion, the sensory info is transmitted neurologically to and processed within the mind,” Stensland mentioned. “The mind and physique are alarmed. Neurological sensitivity is mostly elevated, stress hormones are launched and our protection system [immune system] is modulated.”

          All of that, she defined, might make the mind “hypersensitive,” rendering an individual extra susceptible to ache.

          Different points, resembling sleep issues, might add on to the consequences, Stensland famous.

          Copyright © 2017 HealthDay. All rights reserved.

          SOURCES: Synne Oien Stensland, M.D., Ph.D., Norwegian Heart for Violence and Traumatic Stress Research, Oslo College Hospital, Oslo, Norway; Matthew Robbins, M.D., director, inpatient companies, Montefiore Headache Heart, and affiliate professor, medical neurology, Albert Einstein Faculty of Medication, Montefiore Well being System, New York Metropolis; Dec. 13, 2017, Neurology, on-line

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            Picky eaters and how to cope with them over the holidays

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            2015 WebMD Health Hero Awards Presenter Seth Rogen

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            Comedy superstar Seth Rogen presents the award for 2015 WebMD Health Hero, Prodigy, to 17-year-old Kenneth Shinozuka, at this year’s awards gala November 5, 2015, at the Times Center in New York City.

            Seth Rogen and his wife, Lauren, founded Hilarity for Charity — an organization determined to inspire change and raise awareness of Alzheimer’s Disease among the millennial generation — to show people how important it is to end Alzheimer’s, while having a little fun along the way. Hilarity for Charity is fueled by the philosophy that there are many different ways to deliver a message, and that even the most serious information can be transmitted through humor.


            Medical Videos – 2015 WebMD Health Hero Awards Presenter Seth Rogen #Medical #Videos