With IVF, Are Fresh or Frozen Embryos Better?

News Picture: With IVF, Are Fresh or Frozen Embryos Better?

THURSDAY, Jan. 11, 2018 (HealthDay News) — The chances of having a baby after in vitro fertilization (IVF) are similar for most women whether frozen or fresh embryos are used, a new study finds.

In a group of infertile women with normal ovulation, rates of live birth were nearly 49 percent in those who received frozen embryos. Rates were just over 50 percent for women who received fresh embryos, said researchers at Penn State College of Medicine.

The study included more than 2,100 women undergoing their first round of IVF. The treatment involves fertilizing a woman’s egg with sperm in a laboratory dish. The resulting embryo is then inserted in the woman’s uterus.

Previous research by this team found that women with polycystic ovarian syndrome — abnormal ovulation — fared better with frozen embryos.

But it wasn’t clear whether fresh and frozen embryos offered better chances of success in women who ovulate normally, the study authors explained.

“This is an important and distinct finding from our previous IVF study, and it suggests that one type of IVF treatment does not fit all, and treatments should be chosen based on specific patient characteristics,” said researcher Richard Legro. He’s a professor of obstetrics and gynecology and public health sciences.

Researchers also found that women who received frozen embryos had a lower risk of condition called ovarian hyperstimulation syndrome. This sometimes develops in women undergoing fertility treatment. Serious illness or death can occur in severe cases.

“This study reinforces our previous research by noting that the elective freezing of embryos is safer for all IVF patients… by reducing the risk of ovarian hyperstimulation syndrome,” Legro said in a college news release.

The findings were published Jan. 10 in the New England Journal of Medicine.

— Robert Preidt

MedicalNews
Copyright © 2018 HealthDay. All rights reserved.

SOURCE: Penn State, news release, Jan. 10, 2018

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    Annual Flu Pictures Assist Hold Seniors Out of the Hospital

    News Picture: Annual Flu Shots Help Keep Seniors Out of the HospitalBy Maureen Salamon
    HealthDay Reporter

    Newest Senior Well being Information

    MONDAY, Jan. eight, 2018 (HealthDay Information) — The present flu season is shaping as much as be a nasty one, however there’s excellent news for American seniors who’ve gotten their flu shot.

    New analysis exhibits that for older adults, faithfully getting the vaccine every year vastly reduces the percentages of catching a flu so extreme that it lands you within the hospital.

    Researchers discovered that repeated influenza vaccination gives a double profit in older adults, proving 74 p.c efficient in stopping intensive-care (ICU) admissions and 70 p.c efficient in stopping deaths.

    The findings bolster the notion that though getting a flu shot does not at all times stop the flu, it might make it milder for many who do catch it, mentioned research writer Dr. Jesus Castilla. He is a researcher on the Navarra Institute for Well being Analysis in Pamplona, Spain.

    “We have been stunned by the large magnitude of the vaccine impact in stopping extreme influenza,” Castilla mentioned. “Our outcomes present the significance of annual vaccination for stopping extreme influenza within the older inhabitants.”

    “The prevention of extreme influenza was primarily noticed in sufferers repeatedly vaccinated in each the present and former [flu] seasons, which reinforces the advice of annual influenza vaccination within the aged,” he added.

    Tens of millions of People catch the flu yearly, leading to a whole bunch of 1000’s of hospitalizations, in response to the U.S. Facilities for Illness Management and Prevention. Flu-related deaths ranged from 12,000 to 56,000 yearly between 2010 and 2017, in response to CDC estimates.

    Older adults, whose immune techniques aren’t as strong, are extra liable to struggling extreme outcomes from flu an infection, together with hospitalization, problems and dying, Castilla famous.

    “Annual vaccination acts as a booster for his or her immune response,” he mentioned. “In different phrases, the safety will increase as in comparison with the impact of vaccination in a single season.”

    The brand new analysis by Castilla and his colleagues concerned a whole bunch of hospitalized sufferers, older than 65, who had influenza — each extreme and fewer extreme instances — in addition to those that didn’t.

    Individuals who’d gotten a flu vaccination within the present and three earlier flu seasons have been half as more likely to develop a extreme case of the flu, the research discovered.

    “I feel it is reassuring that what we advocate individuals to do — which is to get vaccinated yearly — really does present some extra safety,” mentioned Dr. Marci Drees, who was not concerned with the brand new research. She’s an an infection prevention officer and hospital epidemiologist with Christiana Care Well being System in Wilmington, Del.

    “An important take-home message is to get your flu shot and never fear about how efficient it’s this 12 months,” Drees added, referring to issues that the present U.S. vaccine could be solely marginally efficient.

    “Individuals could be extra inclined to skip it, however this research actually emphasizes main profit is 12 months after 12 months of persistently getting that flu shot helps hold individuals out of the hospital and ICU,” she mentioned.

    Growing every year’s flu vaccine is a difficult enterprise, Drees defined. Well being officers within the Northern Hemisphere examine what strains of the virus circulated most generally within the Southern Hemisphere in earlier months after which adapt the vaccine to these expectations.

    “They should do some little bit of guesswork . . . and do not at all times guess appropriately,” she mentioned.

    Latest research present that flu vaccination cuts the chance of flu sickness by 40 to 60 p.c among the many common inhabitants.

    Drees mentioned she’d prefer to see analysis concentrate on youthful populations, together with kids, to find out if comparable safety is conferred after repeated vaccinations.

    “You are boosting your immune system each time you get that vaccination,” she mentioned. “We all know immunity wanes extra shortly in older individuals, so getting that increase 12 months after 12 months might be contributing to the safety we have seen towards extreme illness.”

    The research is revealed on-line Jan. eight within the journal CMAJ.

    MedicalNews
    Copyright © 2018 HealthDay. All rights reserved.

    SOURCES: Jesus Castilla, M.D., Ph.D., researcher, Navarra Institute for Well being Analysis, Pamplona, Spain; Marci Drees, M.D., M.S., an infection prevention officer and hospital epidemiologist, Christiana Care Well being System, Wilmington, Del.; CMAJ, Jan. eight, 2018, on-line

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